| 초록 |
Advanced glycation end products (AGEs) have been implicated in diabetic complications. In this study, the inhibitory effect on AGEs formation of 156 Korean herbal medicines has been evaluated. Among them, 15 Korean herbal medicines were showed to have significant effect (IC 50 : #60;10 #956;g/ml) compared to positive reference, aminoguandine (IC 50 : 76.47 #xb1;4.81 #956;g/ml). Especially, four herbal medicines, Alnus firma (leaves, IC 50 : 3.25 #xb1;0.10 #956;g/ml), Juncus decipiens (whole plants, IC 50 : 4.30 #xb1;0.44 #956;g/ml), Smilax china (stems, IC 50 : 3.55 #xb1;0.21 #956;g/ml), and Vicia amoena (Aerial parts, IC 50 : 4.25 #xb1;0.06 #956;g/ml) showed more potent inhibitory activity approximately 8-24 fold) than the positive control aminoguanidine. |
