초록 |
Clinically, three holstein dairy cattle showed the inappetence and decrease of milk production with severe lameness and pain. Grossly, strawberry-like proliferation of the skin between the heel bulbs were observed 4 ${ times}$ 5 ${ times}$ 1.5cm in size. Histopathologically, severe hyperplasia of epidermis, parakeratotic hyperkeratosis and multifocal ulceration of cornified cell layer, acanthosis, spongiosis of prickle cell layer and irregular arrangement of basal cell layer were seen. And focally observed the lesions of necrotic vasculitis, infiltration of inflammatory cells, congestion and hemorrhage. Spirochete bacteria were found in necrotic and outer proliferated epidermal cells by Levaditi's silver stain. Clinical and pathological findings were consistent with dermatitis verrucosa. |