| 저자(한글) |
ZHANG, Xiaobing,GONG, Yali,LIU, Zhiyong,YUAN, Hongying,FU, Weiling |
| 초록 |
OBJECTIVE To investigate the drug susceptibility of clinical isolates in local region for using antibiotic reasonably. METHODS Totally 3 170 strains of clinical isolates were identified by API and Microscan and tested for drug resistance against antimicrobial agents by K-B method. WHONET5. 4 was applied for analysis. RESULTS The commonly encountered bacteria were Pseudomonas aeruginosa (24.3 %), Acinetobacter baumannii (10.9%), K lebsiella pneumoniae (10.4%), Escherich ia coli (8.9%), and Staphylococcus aureus (SA,8.0%). In Gram-negative isolates, the resistance rate to meropenem was 19. 7%, and to piperacillin-tazobactam was 26.5%. The incidences of E. coli and K. pneumoniae isolates producing extended spectrum beta-lactamases (ESBLs) were 49.1% and 33.5%, respectively. In Gram-positive isolates, the susceptibility rate to vancomycin and teieoplanin both was 100. 0%. The oxacillin resistant rates of SA and coagulase negative Staphylococcus (CNS) were 54. 2.0% and 82.3%. CONCLUSIONS The production ratio of ESBLs and oxaeillin resistance of bacteria in local region are high. It is important to promote the rational use of antimicrobial agents and take effective contaminant methods to reduce resistant rates of bacteria and dissemination of multi-resistant bacteria. |
