| 저자(한글) |
Do, Jung-Ah,Kim, Jung Yeon,Choi, Ji Yeon,Lee, Ji Hyun,Kim, Hyung Joo,Noh, Eunyoung,Cho, So-Hyun,Yoon, Chang-Yong,Kim, Woo-Seong |
| 초록 |
Recently, the consumption of dietary supplements has increased because of people #x2019;s greater interest in health. Unfortunately, the sales of dietary supplements containing unauthorized substances such as drugs have also increased. We developed a rapid, accurate method for the simultaneous determination of antihistamines using liquid chromatography tandem mass spectrometry with a multiple reaction monitoring mode. The limit of detection (LOD) and limit of quantification (LOQ) of the instrument used in this method were in the ranges 0.0003-0.3 and 0.0009-0.6 #xB5;g mL #x2212;1 , respectively. The linearity of the method was #x3E; 0.99. The precision levels of the method were 0.1-9.8% (intra-day) and 0.3-9.6% (inter-day), and the levels of accuracy of the method were 82.7-115.0% (intra-day) and 84.3-113.0% (inter-day). The mean of recovery of the method was in the range of 83.9-117.9% and the RSD of the stability was less than 5.9%. |
