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흰 무궁화 꽃 추출물의 항산화 활성과 골 흡수의 억제 효과
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 韓國藥用作物學會誌 = Korean journal of medicinal crop science |
| ISSN | 1225-9306, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | 이희정,이상원,박춘근,안영섭,김진성,방만석,오충훈,김철태 |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2015-01-01 |
| 초록 | In this study, we tried to offer the possibility of White Hibiscus syriacus L. (WHS) flower extracts as a preventive and improving agent of osteoporosis that bone mass reduction is induced by an decrease of osteoblast involved in bone formation and increase of bone resorption by osteoclast activity. As a results, it was found to have antioxidant activity and contain a flavonoid contents ($47.74 mg/g) of the WHS flower. There was cytotoxicity at more than $250{ mu}g/m{ ell}$ concentration of WHS flower extract of RANKL-induced osteoclast in RAW264.7. There were no significant inhibited TRAP activity in the WHS leaf and stem. However, it was confirmed that it is significantly inhibited the differentiation activity of osteoclasts in 50 and $100{ mu}g/m{ ell}$ concentration of cells of stability levels of only WHS flower extracts (p |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO201520441373345 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
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| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | white Hibiscus syriacus L.,Flavonoid,Antioxidant Activity,Osteoporosis,Osteoclast,Osteoblast |