| 초록 |
Background: The biological activities of Tradescantia pallida grown in Korea have not been well determined, thus the aim of this study was to investigate the possibility of using it as a medicinal plant. Methods and Results: To investigate the antioxidant activity, ${ alpha}$ -glucosidase inhibitory effect and antimicrobial activity of T. pallida, we performed the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity and reducing power assay. This assay for T. pallida leaf extract showed the highest antioxidant activity for the ethyl acetate fraction ( $RC_{50}=14.55{ pm}0.16{ mu}g/m{ ell}$ and Abs = 0.613 at $300{ mu}g$ ). Further, the ethyl acetate fraction exhibited higher ${ alpha}$ -glucosidase inhibitory effect with an $IC_{50}$ value of $14.1{ pm}0.1{ mu}g/m{ ell}$ and showed antimicrobial activity against gram positive bacteria (minimum inhibitory concentration = $1,000{ mu}g/m{ ell}$ ). Conclusions: The ethyl acetate fraction of the crude methanol extract of T. pallida showed remarkable antioxidant activity, ${ alpha}$ -glucosidase inhibitory effects and antimicrobial activity. These activities might be related to the flavonoid content in the T. pallida leaf extract. |
