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녹차씨 주정추출물의 카페인 함량 평가와 고지방식이 비만유도 C57BL/6 마우스와 3T3-L1 지방전구세포의 항비만효과
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 동의생리병리학회지 = Journal of physiology pathology in Korean Medicine |
| ISSN | 1738-7698,2283-2529 |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | 정명아,이현미,오둘리,김유진,배동혁,오교녀,신희찬,김선오 |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2016-01-01 |
| 초록 | The study was carried out to examine the anti-obesity effects of 40% ethanol extract from green tea seed (GS) and quantitative determination of caffeine as its major compound. The specificity was satisfied with retention time and UV spectrum by analysis of caffeine using HPLC and comparison with standard compound. It showed a high linearity in the calibration curve with a coefficient of correlation (R 2 ) of 0.9974. The amount of caffeine in GS was about 4.649 mg/g (0.465%) in the three times analysis, and relative standard deviation (RSD) was less than 0.452% by the validated method. The anti-obesity effects of GS were evaluated by using Oil Red O staining in 3T3-L1 adipocytes and body weight, visceral fat and lipid profiles in high fat diet (HFD)-induced C57BL/6 obese mice. Our results indicated that treatment with GS dose-dependently decreased lipid accumulation contents (p |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO201614735110133 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
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| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | Green tea seed,Caffeine,3T3-L1,High fat diet,Cholesterol,Visceral fat |