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논문 기본정보
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논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 한국기계가공학회지 = Journal of the Korean Society of Manufacturing Technology |
| ISSN | 1598-6721,2288-0771 |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | 전현애,이승욱,권오형 |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2014-01-01 |
| 초록 | Poly(g-glutamic acid) (g-PGA) is a very promising biodegradable polymer that is produced by microorganism of Bacillus subtilis. Because g-PGA is water-soluble, anionic, biodegradable, and even edible, its potential applications have been studied from an industrial standpoint. In this study, we fabricated porous g-PGA foams by means of a freeze-solvent extraction method for tissue-engineering applications. Porous g-PGA foams were chemically cross-linked using a hexamethylene diisocyanate solution. An aqueous basic solution was used to neutralize g-PGA foam for cell culturing. During an in vitro cell culture study, it was observed that primary rabbit ear chondrocytes were well at tached and spread over the surface oft hree-dimensional cross-linkedg-PGA foam. From these results, it is concluded that cross-linkedg-PGA foam is aprom is in gmaterial for tissue-engineering applications, especially those pertaining to the regeneration of human cartilage. |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO201421154209301 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | 폴리감마글루탐산,다공성 지지체,동결-용매추출법,생체조직공학,연골세포,Poly( lt,TEX gt,${ gamma}$ lt,/TEX gt,-glutamic acid),Porous Scaffold,Freeze-Solvent Extraction method,Tissue Engineering,Chondrocyte |