배암차즈기(Salvia plebeia R.) 에탄올 추출물의 항산화 및 항알레르기 효과
기관명 | NDSL |
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저널명 | 생약학회지 |
ISSN | 0253-3073, |
ISBN |
저자(한글) | 최봉겸,이선혜,김남석,조수연,장환희,김정봉,이영민,윤순근,이성현 |
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저자(영문) | |
소속기관 | |
소속기관(영문) | |
출판인 | |
간행물 번호 | |
발행연도 | 2014-01-01 |
초록 | The Salvia plebeia R. which is the biennial plant belonging to the labiatae department, grows widely in Korea. This study was performed to evaluate the antioxidant activities and anti-allergic effects of Salvia plebeia R. leaves (SPLE) or roots (SPRE). Using ethanol extracts, both leaves and roots induced significant radical scavenging activity against DPPH and ABTS radicals in a dose dependent manner (p ${ beta}$ -Hexosaminidase release and significantly inhibited IgE-antigen complex-mediated IL-4 and TNF- ${ alpha}$ mRNA expression in RBL-2H3 cells. These findings suggest that Salvia plebeia R. can protect or reduce allergic asthma through high antioxidant and anti-allergic reactions. |
원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO201402852974150 |
첨부파일 |
과학기술표준분류 | |
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ICT 기술분류 | |
DDC 분류 | |
주제어 (키워드) | Salvia plebeia R.,Anti-oxidative,Anti-allergic,Asthma,RBL-2H3 |