Circulating endothelial cells and serum visfatin are indicators of cardiovascular disease risk in psoriasis patients
기관명 | NDSL |
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저널명 | 中華皮膚科醫學雜誌 = Dermatologica Sinica |
ISSN | 1027-8117, |
ISBN |
저자(한글) | Elgarhy, L.,Abdelnabi, N.,Abdullatif, A.,Attia, M.,Mabrouk, M.M.,El Sheikh, E. |
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저자(영문) | |
소속기관 | |
소속기관(영문) | |
출판인 | |
간행물 번호 | |
발행연도 | 2016-01-01 |
초록 | Background: Cardiovascular risk in psoriasis (PS) appears to be dependent on disease severity. Circulating endothelial cell (CEC) counts appear to be elevated in numerous conditions associated with endothelial dysfunction including chronic immune-mediated inflammatory disorders. Adipokines could serve as a missing link between PS and comorbidities Aim: To evaluate the numbers of CECs and serum visfatin levels in PS patients in comparison to controls to investigate their possible role in increased cardiovascular disease (CVD) risk. Methods: Twenty-five PS patients and 15 healthy individuals were recruited. CECs numbers were detected in peripheral blood samples through studying CD146 and CD45 expression by flow cytometry. Serum visfatin levels were detected by enzyme-linked immunosorbent assay. Results: There was a statistically significant increase in CEC numbers and serum visfatin levels in PS patients compared to controls (p |
원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART75052318 |
첨부파일 |
과학기술표준분류 | |
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ICT 기술분류 | |
DDC 분류 | |
주제어 (키워드) | endothelial cells,psoriasis,visfatin |