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논문 기본정보
Eradication Rate of Helicobacter pylori According to the Diseases and Therapeutic Regimens, and Reinfection Rate after Successful Eradication in a Tertiary Clinic
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 대한소화기학회지 = The Korean journal of gastroenterology |
| ISSN | 1598-9992, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | Chung, Woo Chul,Cho, Young Seok,Jeong, Joeng Jo,Lee, In Seok,Kim, Sang Woo,Yang, Jin Mo,Choi, Myung Gyu,Chung, In Sik,Park, Doo Ho |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2003-01-01 |
| 초록 | BACKGROUND/AIMS: Controversies regarding the indications and regimens for the eradication of Helicobacter pylori (H. pylori) still exist. Failure rates have been reported to range from 5% to 10%. This study aimed to review the efforts for the eradication of H. pylori in a tertiary clinic. We assessed the eradication rates according to the diseases, therapeutic regimens, and duration of therapy. In addition, we examined the effectiveness of secondary regimens in patients who failed to respond to primary regimens and the reinfection rate after a successful eradication. METHODS: We investigated 389 patients with documented H. pylori infection between January 1996 and December 2001. RESULTS: The overall eradication rate was 79.2%. There were no significant differences in the eradication rates sccording to the diseases and therapeutic regimens. However, there was a significant difference according to the duration of therapy. Proton pump inhibitor (PPI)-based 10-day and 14-day regimens were superior to 7-day regimens. The eradication rate of secondary regimens in patients who failed to respond to primary regimens was 76.9%. The reinfection rate after a successful eradication was 4.4%. CONCLUSIONS: These results suggest that PPI-based triple regimens with 10 or 14 days of duration should be considered as primary H. pylori eradication therapy. |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART48216758 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | Helicobacter pylori,Eradication rate,Reinfection rate |