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논문 기본정보
실험적으로 동맥경화증을 유발시킨 랫드에서 lt;TEX gt;${ beta}$ lt;/TEX gt;-Glucan의 동맥경화 방어기전에 대한 연구
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology |
| ISSN | 1225-6110, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | 김형욱,이영순 |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 1993-01-01 |
| 초록 | Mechanisms for the hypocholesterolemic effetcs of $ beta$ -glucan remain unclear. Rats were divided into 3 groups; normal control group, atherogenic group(oral administration of cholesterol 40 mg/kg/day and vitamin $D_2$ 320,000 IU/kg/day), ${ beta}$ -glucan treatment group(oral administration of atherogenic treatment and ${ beta}$ -glucan 0.135 g/kg/day). The ${ beta}$ -glucan treatment group showed moderate increases of serum lipids concentration compared with atherogenic group. In histopathological examination, aortas showed no critical lesions. The total fecal neutral sterols and bile acids excreted for 6 days was increased compared with both normal and atherogenic group. These result ulcorner suggest that mechanisms for the hypocholesterolemic effect of ${ beta}$ -glucan on rats were due to the inhibition of cholesterol absorption in the intestinal lumen and acceleration of cholesterol catabolism in the liver. |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO199311920959003 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | atherosclerosis, lt,TEX gt,${ beta}$ lt,/TEX gt,-glucan,dietary fiber,cholesterol excretion,gas-liquid chromatography |