랫드와 마우스에서 DA-3030(G-CSF)의 급성독성에 관한 연구
기관명 | NDSL |
---|---|
저널명 | The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology |
ISSN | 1225-6110, |
ISBN |
저자(한글) | 이영순,조재진,김영석,남정석,박재학,이순복 |
---|---|
저자(영문) | |
소속기관 | |
소속기관(영문) | |
출판인 | |
간행물 번호 | |
발행연도 | 1994-01-01 |
초록 | This study was performed to evaluate the acute toxicity of DA-3030(granulocyte-colony stimulating factor, G-CSF) in mice and rats via intragastrical and intravenous routes. DA-3030(G-CSF) in the acute toxicity study did not induce any toxic signs in the mice and rats in mortalities, clinical findings, body weights and gross findings. It is suggested that LD $_{50}$ values in mice and rats would be gt;13, 800 $ mu textrm{g}$ /kg in the oral route and gt;6, 900 $ mu textrm{g}$ /kg in the intravenous route.e. |
원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO199411920961743 |
첨부파일 |
과학기술표준분류 | |
---|---|
ICT 기술분류 | |
DDC 분류 | |
주제어 (키워드) | DA 3030,granulocyte colony stimulating factor,acute toxicity, lt,TEX gt,$LD_{50}$ lt,/TEX gt |