Prostaglandin lt;TEX gt;$F_2{ alpha}$ lt;/TEX gt; Controls Reactive Oxygen Species in Bovine Corpus Luteum
기관명 | NDSL |
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저널명 | Reproductive developmental biology = 한국동물번식학회지 |
ISSN | 1738-2432, |
ISBN |
저자(한글) | Lee, Seunghyung,Yang, Boo-Keun,Park, Choon-Keun |
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저자(영문) | |
소속기관 | |
소속기관(영문) | |
출판인 | |
간행물 번호 | |
발행연도 | 2015-01-01 |
초록 | Luteolysis is a cyclical regression of the corpus luteum in many non-primate mammalian species. Prostaglandin $F_2{ alpha}$ ( $PGF_2{ alpha}$ ) from the uterus and ovary induces functional and structural luteolysis in bovine. The action of $PGF_2{ alpha}$ is mediated by $PGF_2{ alpha}$ receptor located on the luteal steroidogenic and endothelial cell membranes. $PGF_2{ alpha}$ plays an important role in regulating nitric oxide production in endothelial cells of the bovine corpus luteum. Nitric oxide production and nitric oxide synthase activity are stimulated and induced by $PGF_2{ alpha}$ in luteal endothelial cells. Moreover, the reactive oxygen species inhibits progesterone secretion in bovine luteal cells and induces apoptosis. Thus, the interaction between $PGF_2{ alpha}$ and reactive oxygen species provides important aspects in physiology of the corpus luteum forfunctional and structural luteolysis. |
원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO201509162415835 |
첨부파일 |
과학기술표준분류 | |
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ICT 기술분류 | |
DDC 분류 | |
주제어 (키워드) | Prostaglandin lt,TEX gt,$F_2{ alpha}$ lt,/TEX gt,. Reactive oxygen species,Corpus luteum,Steroidogenic luteal cell,Endothelial cell |