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논문 기본정보
Hypopigmented mycosis fungoides: An immunological investigation of tumor-infiltrating T cells
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 中華皮膚科醫學雜誌 = Dermatologica Sinica |
| ISSN | 1027-8117, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | Nasu-Tababuchi, M.,Fujimura, T.,Kakizaki, A.,Shido, K.,Hatchome, N.,Kusakari, Y.,Aiba, S. |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2016-01-01 |
| 초록 | Hypopigmented mycosis fungoides (HMF) is a clinical variant of MF presenting a good prognosis. In this report, we describe a case of HMF with dense infiltration of tumor-infiltrating leukocytes that bear several cytotoxic molecules, such as granulysin and T-cell intracellular antigen-1. In addition, our immunohistochemical study revealed that the ratio of Foxp3 + regulatory T cells to the total CD4 + cells is decreased in the lesional skin of HMF, compared with that of conventional MF. Our case suggested possible mechanisms for the hypopigmentation and good prognosis of this type of MF. |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART75679102 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | cytotoxic molecules,hypopigmented mycosis fungoides,regulatory T cells,tumor-infiltrating leukocytes |