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논문 기본정보
Flow-through Hybridization and Its Clinical Application to Human Papillomavirus Subtype Detection
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 中華醫院感染學雜志 = Chinese journal of nosocomiology |
| ISSN | 1005-4529, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | CHEN, Zhan-guo,ZHOU, Wu,XU, Zhang-ye,DAI, Mei-jie,TAO, Zhi-hua |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2008-01-01 |
| 초록 | OBJECTIVE To evaluate the clinical application of flow-through hybridization to human papillomavirus (HPV) subtype detection. METHODS A total of 305 female patients infected with HPV were selected for HPV subtype analysis using flow-through hybridization and the assessment of HPV subtype on cervical lesions was analyzed. RESULTS All 21 different subtypes were found. From 305 cases 173 patients were infected with single- type HPV and 132 patients were infected with multiple-type HPV. The most commonly found high-risk types were HPV16(17.6%), HPV52(9.8G), HPV58(9.0%), HPV33(6.3%), HPV18(5.4%) and HPV68(5.2%) and the low-risk types were HPV11(14.3%) and HPV6(6. 5%). The high-risk HPV increased and the low-risk HPV declined along with the upgrade of the cervical lesions. CONCLUSIONS Technology of flow-through hybridization is able to detect multiple HPV subtype. The distinction between low and high-risk HPV subtypes is seemed useful in prevention and management of cervical cancer. |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART51531260 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
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| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | Human papillomavirus,Subtype,Hybridization,Infection |