| 초록 |
OBJECTIVE To evaluate mortality prediction by analyzing clinical features and pathogens of patients with candidemia in intensive care unit (ICU). METHODS The clinical data of candidemia cases admitted to ICU of the First Affiliated Hospital of Zhejiang University in recent five years were analyzed retrospectively, including risk factors, accompanied diseases, Candida species, drug sensitivity, mortality and prognosis. RESULTS Seventy five cases with candidemia were diagnosed in recent five years. Single factor Logistic regression analysis combined with multiple conditional Logistic regression model analysis was conducted. Compared to other risk factors, indwelling central venous catheter(97. 2% vs 74. 3%,P=0. 043,OR=6. 4,95%CI 1. 06-38. 72), hypoproteinemia (91.7% vs 56. 4% ,P=0. 020,OR=6.01,95%CI 1.33-27.0)and APACHE Ⅱ score (19.6±3.7 vs 15.0±3. 8,P=0.00,OR=1. 36,95% CI 1. 15-1.62) were markedly different. CONCLUSIONS Candidemia cases in ICU increase gradually and lead to higher mortality. Indwelling central venous catheter, hypoproteinemia and APACHE Ⅱ score are related to mortality of candidemia cases. |
