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논문 기본정보
Intralipidos에 대한 변이원성시험
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | Journal of toxicology and public health : an official journal of the Korean Society of Toxicology |
| ISSN | 1226-8399, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | 정지윤,이원우,임종희,남정석,제정환,이광훈,강병철,이병희,박재학,이영순 |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 1998-01-01 |
| 초록 | In order to evaluate the mutagenic potential of Intralipidos produced by Greenmate cooperation. We performed Salmonella typhimurium reversion assay, chromosomal aberration test on chinese hamster ovarian cells and in vivo micronucleus assay using mouse bone marrow cells. In the reverse mutation test using Salmonella typhimurium TA98 and TA100, Intralipidos did not increase the number of revertant at any of the concentration tested in this study. Intralipidos did not increase the number of cells having structural or numberical chromosome aberration in cytogenetic test. In mouse micronucleus test, no significant increase were observed in the occurrence of micornucleated polychromatic erythrocytes in ICR male mice intraperitoneally administered with Intralipidos. These results indicate that Intralipidos has no genetic toxicity under these experimental conditions. |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=JAKO199815875822755 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | Salmonella typhimurium reversion assay,Chromosomal aberration test,Micronucleus assay,Intralipidos |