저자(한글) |
김우진,심주철,공보금,강제욱,문정준,김정은,김민걸,박민경,김성진,김현정,정도운 |
저자(영문) |
|
소속기관 |
|
소속기관(영문) |
|
출판인 |
|
간행물 번호 |
|
발행연도 |
2011-01-01 |
초록 |
nbsp; nbsp;Objectives:This study was to identify weight amp; metabolic changes in first-episode psychotic patients with antipsychotics use and investigate the differences of weight amp; metabolic changes between first-episode psychotic patients and controls with antipsychotics use. nbsp; nbsp;Method:In this retrospective study, twenty eight first-episode psychotic patients and twenty eight controls with schizophrenia, schizoaffective or bipolar disorder defined by DSM-IV criteria were included. Information about demographic and clinical characteristics of the subjects was gathered from the medical records. Also body weight, sBP, dBP, fasting glucose, lipid profile and WBC count were evaluated before and after antipsychotics use. Rogistic regression was conducted to assess factors associated with weight gain. nbsp; nbsp;Results:First-episode psychotic patients showed more weight and BMI changes than controls after antipsychotics use, and these changes continue over 12 months. On the other hand, there were no significant factors associated with weight gain. nbsp; nbsp;Conclusion:The results of present study suggest that antispychotics is one of the major causes inducing weight gain of psychotic patients and antipsychotics-induced weight gain is more vulnerable to drug-naive first-episode psychotic patients. |
원문URL |
http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART69863464 |
첨부파일 |
|