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논문 기본정보
Variation of Pediatric Clinical Bacterial Isolates and Antibiotic Resistance in Hubei Area
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | 中華醫院感染學雜志 = Chinese journal of nosocomiology |
| ISSN | 1005-4529, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | FANG, Hong,LI, Xiuyun,WANG, Hongwei,SUN, Ziyong,DU, Pengchao |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2008-01-01 |
| 초록 | OBJECTIVE To investigate the distribution of pediatric clinical bacterial isolates and the change in antibiotic resistance spectrum in Hubei area during 6 years. METHODS Data of bacterial susceptibility testing of clinical isolates from 15 tertiary hospitals in Hubei area from 1999 to 2004 were collected and analyzed by software WHONET-5. Results were assessed according to NCCLS 2002. RESULTS The amount of Gram-negative bacteria went down and of Gram-positive bacteria went up during this period. The proportion of coagulase-negative Staphylococcus (CNS) had been increasing and reached 32. 4% in 2004. The proportions of Staphylococcus aureus decreased from 15.7% in 1999 to 7.4% in 2004. Escherichia were the second bacteria in the last two years. The drug resistance rate of staphylococci against penicillin and erythromycin was more than 94% and 58%, respectively. The oxacillin resistance rate of CNS was 74 %, significantly higher than that of S. aureus (16. 5 % ). Drug resistance rate of Enterococcus to vancomycin was 2. 1%. Gram-negative bacteria were sensitive to meropenem and imipenem, whereas the resistance rate of Klebsiella and Escherichia to ampicillin was 98.1% and 85. 1%, respectively. CONCLUSIONS The variation of drug resistance and distribution of pediatric clinical bacterial isolates are related to the improper use of antibiotics. It is very important to select antibiotics correctly according to the results of susceptibility tests. |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART51531014 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | Pathogen,Children,Drug resistance |