- HOME
- 홈페이지 이용안내
논문 기본정보
Physicochemical properties and bioactivity of freeze-cast chitosan nanocomposite scaffolds reinforced with bioactive glass
논문 개요
| 기관명 | NDSL |
|---|---|
| 저널명 | Materials science engineering. C, Materials for biological applications |
| ISSN | 0928-4931, |
| ISBN |
논문저자 및 소속기관 정보
| 저자(한글) | Pourhaghgouy, M.,Zamanian, A.,Shahrezaee, M.,Masouleh, M.P. |
|---|---|
| 저자(영문) | |
| 소속기관 | |
| 소속기관(영문) | |
| 출판인 | |
| 간행물 번호 | |
| 발행연도 | 2016-01-01 |
| 초록 | Chitosan based nanocomposite scaffolds were prepared by freeze casting method through blending constant chitosan concentration with different portions of synthesized bioactive glass nanoparticles (BGNPs). Transmission Electron Microscopy (TEM) image showed that the particles size of bioactive glass (64SiO 2 .28CaO.8P 2 O 5 ) prepared by sol-gel method was approximately less than 20nm. Fourier Transform Infrared Spectroscopy (FT-IR) and X-ray Diffraction (XRD) analysis showed proper interfacial bonding between BGNPs and chitosan polymers. Scanning Electron Microscopy (SEM) images depicted a unidirectional structure with homogenous distribution of BGNPs among chitosan matrix associated with the absence of pure chitosan scaffold's wall pores after addition of only 10wt.% BGNPs. As the BGNP content increased from 0 to 50wt.%, the compressive strength and compressive module values increased from 0.034 to 0.419MPa and 0.41 to 10.77MPa, respectively. Biodegradation study showed that increase in BGNP content leads to growth of weight loss amount. The in vitro biomineralization studies confirmed the bioactive nature of all nanocomposites. Amount of 30wt.% BGNPs represented the best concentration for absorption capacity and bioactivity behaviors. |
| 원문URL | http://click.ndsl.kr/servlet/OpenAPIDetailView?keyValue=03553784&target=NART&cn=NART73259652 |
| 첨부파일 |
추가정보
| 과학기술표준분류 | |
|---|---|
| ICT 기술분류 | |
| DDC 분류 | |
| 주제어 (키워드) | Bioactive glass nanoparticles,Chitosan,Freeze casting,Nanocomposite,Scaffold,Bone tissue engineering |